INT18801

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Context Info
Confidence 0.43
First Reported 1990
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adra2a) plasma membrane (Adra2a) cytoplasm (Adra2a)
signal transducer activity (Adra2a)
Anatomy Link Frequency
vena cava 2
respiratory 2
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
noradrenaline 2 99.54 Very High Very High Very High
Clonidine 8 98.72 Very High Very High Very High
agonist 4 76.40 Quite High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the rat vena cava preincubated with [3H]-noradrenaline, the B-HT 920-induced alpha 2-adrenoceptor-mediated inhibition of electrically evoked tritium overflow was also reduced at lower temperature. 5.
Negative_regulation (reduced) of Negative_regulation (inhibition) of alpha 2-adrenoceptor-mediated in vena cava associated with noradrenaline
1) Confidence 0.43 Published 1990 Journal J Auton Pharmacol Section Abstract Doc Link 1982111 Disease Relevance 0 Pain Relevance 0.30
Blockade of alpha2-adrenergic receptors with intravenous doses of SKF 86466 (200 microg kg(-1)) abolished all respiratory effects of the clonidine challenge.
Negative_regulation (abolished) of Negative_regulation (Blockade) of alpha2-adrenergic in respiratory associated with clonidine
2) Confidence 0.42 Published 2006 Journal Exp. Physiol. Section Abstract Doc Link 16282369 Disease Relevance 0 Pain Relevance 0.61

General Comments

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