INT188050

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Context Info
Confidence 0.37
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 3.13
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Anatomy Link Frequency
chondrocytes 2
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 27 99.98 Very High Very High Very High
Inflammation 45 89.04 High High
Nicotine 9 87.92 High High
Hippocampus 31 71.12 Quite High
cytokine 16 52.52 Quite High
Central nervous system 24 50.68 Quite High
fibrosis 2 31.12 Quite Low
Kinase C 43 5.00 Very Low Very Low Very Low
depression 18 5.00 Very Low Very Low Very Low
Osteoarthritis 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 50 98.56 Very High Very High Very High
Hypertrophy 19 93.92 High High
Familial Adenomatous Polyposis 56 93.48 High High
Stress 20 90.20 High High
Drug Induced Neurotoxicity 36 90.08 High High
INFLAMMATION 54 89.04 High High
Alzheimer's Dementia 15 88.60 High High
Apoptosis 97 88.04 High High
Disease 225 86.92 High High
Neurodegenerative Disease 40 85.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cross-talk with other signaling cascades that regulate Wnt/?
Regulation (regulate) of Gene_expression (/) of Wnt
1) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Abstract Doc Link PMC2515306 Disease Relevance 0.52 Pain Relevance 0.09
agonists modulate Wnt signaling components, including the inhibition of GSK-3?
Regulation (modulate) of Gene_expression (components) of Wnt associated with agonist
2) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.55 Pain Relevance 0.13
agonists modulate Wnt signaling components, including the inhibition of GSK-3?
Regulation (signaling) of Gene_expression (components) of Wnt associated with agonist
3) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.54 Pain Relevance 0.13
Differential transcript profiles, possibly relevant to rodent follicular cell tumor outcomes, were observed in rats exposed to PB and PTU, including genes involved in Wnt signaling and ribosomal protein expression.



Regulation (involved) of Gene_expression (expression) of Wnt associated with cancer
4) Confidence 0.25 Published 2005 Journal Environ Health Perspect Section Abstract Doc Link PMC1281279 Disease Relevance 0.37 Pain Relevance 0
The Wnt family of glycoproteins are involved in activation of the Wnt /  ?
Regulation (involved) of Gene_expression (family) of Wnt
5) Confidence 0.09 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 0.49 Pain Relevance 0
In the present study the up-regulation of key components of the wnt- as well as the TGF-?
Regulation (regulation) of Gene_expression (components) of wnt
6) Confidence 0.07 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2915993 Disease Relevance 0.29 Pain Relevance 0.09
The Wnt pathway involves a large network of proteins that can regulate the production of Wnt signaling molecules [2].
Regulation (regulate) of Gene_expression (production) of Wnt
7) Confidence 0.06 Published 2010 Journal Journal of Osteoporosis Section Body Doc Link PMC2957275 Disease Relevance 0 Pain Relevance 0
Hypertrophic differentiation of chondrocytes, as well as bone formation, is also regulated by the Wnt/?
Regulation (regulated) of Gene_expression (/) of Wnt in chondrocytes
8) Confidence 0.04 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206353 Disease Relevance 0.38 Pain Relevance 0
The Wnt pathway involves a large network of proteins that can regulate the production of Wnt signaling molecules and interaction with receptors and target cells, and the physiologic response of target cells that result in exposure of cells to the extracellular Wnt ligands.
Regulation (regulate) of Gene_expression (production) of Wnt
9) Confidence 0.01 Published 2010 Journal Curr Osteoporos Rep Section Body Doc Link PMC2841260 Disease Relevance 0 Pain Relevance 0

General Comments

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