INT188176

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.32
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.75
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CDH5) plasma membrane (CDH5)
Anatomy Link Frequency
tube 2
endothelial cells 2
CDH5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 4 77.52 Quite High
Nicotine 79 5.00 Very Low Very Low Very Low
imagery 14 5.00 Very Low Very Low Very Low
Inflammation 13 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 1 95.64 Very High Very High Very High
Hydrocele 28 85.84 High High
Lymphedema 49 85.28 High High
Hypersensitivity 8 78.28 Quite High
INFLAMMATION 20 77.52 Quite High
Helminth Infection 25 71.60 Quite High
Apoptosis 17 50.00 Quite Low
Filariasis 6 50.00 Quite Low
Fungal Infection 1 44.84 Quite Low
Hyperplasia 2 19.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of the 2,601 events that fell within R1 and were subsequently analyzed for VE-cadherin-PE expression, 2,308 (88.7%) also fell within gate M1 and were considered negative for VE-cadherin expression.
Positive_regulation (negative) of Gene_expression (expression) of VE-cadherin
1) Confidence 0.32 Published 2005 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC1285366 Disease Relevance 0.13 Pain Relevance 0
In order to study the phenotype of CD31+ cells thus obtained, we confirmed the endothelial phenotype of our CD31+ twice-purified hESC-ECs by flow cytometry analysis for the expression of vWF, CD31, and VE-cadherin (BD Biosciences), DiI-ac-LDL uptake assay, and Matrigel tube formation assay as previously described [15].


Positive_regulation (purified) of Gene_expression (expression) of VE-cadherin in tube
2) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2737633 Disease Relevance 0.08 Pain Relevance 0
At the molecular level, doxycycline appeared to act on the adherence junction in the vasculature with increased expression of VE-cadherin, thus maintaining the cell junctions between endothelial cells and reducing their permeability.
Positive_regulation (increased) of Gene_expression (expression) of VE-cadherin in endothelial cells
3) Confidence 0.02 Published 2009 Journal Parasite Immunology Section Body Doc Link PMC2784903 Disease Relevance 0.54 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox