INT188195

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GOPC, MAPK1) cytoplasm (GOPC, MAPK1) nucleoplasm (MAPK1)
mitochondrion (MAPK1) DNA binding (MAPK1) protein complex (MAPK1)
Anatomy Link Frequency
epithelial cells 1
GOPC (Homo sapiens)
MAPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 60 100.00 Very High Very High Very High
agonist 1 88.56 High High
Inflammation 14 50.00 Quite Low
Hippocampus 1 39.36 Quite Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Amyloid Plaque 35 63.32 Quite High
Small Cell Lung Carcinoma 1 54.24 Quite High
Malignant Neoplastic Disease 4 52.80 Quite High
Carcinoma 16 50.96 Quite High
Alzheimer's Dementia 36 50.80 Quite High
INFLAMMATION 22 50.00 Quite Low
Lung Cancer 16 46.20 Quite Low
Stress 17 5.00 Very Low Very Low Very Low
Metaplasia 8 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fibroblasts exhibited a prominent LIF response and a several-fold higher activation of ERK relative to STAT3 by IL-6 cytokines (Fig. 1A, bottom panel), in contrast to normal epithelial cells.
Fig Positive_regulation (activation) of ERK in epithelial cells associated with cytokine
1) Confidence 0.21 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.16 Pain Relevance 0.22
We found that in addition to JNK, ERK and PKB were activated by H2O2 (Fig. 6, A and B).
Fig Positive_regulation (activated) of ERK
2) Confidence 0.02 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427353 Disease Relevance 0.17 Pain Relevance 0

General Comments

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