INT188202

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HBE1, MAPK1) nucleoplasm (MAPK1) mitochondrion (MAPK1)
transport (HBE1) Golgi apparatus (MAPK1) DNA binding (MAPK1)
Anatomy Link Frequency
epithelial cells 1
HBE1 (Homo sapiens)
MAPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 8 78.56 Quite High
cytokine 59 72.64 Quite High
Inflammation 13 50.00 Quite Low
agonist 1 21.08 Low Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 78.56 Quite High
Lung Cancer 16 58.88 Quite High
Carcinoma 16 41.72 Quite Low
Metaplasia 8 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Cleidocranial Dysplasia 4 5.00 Very Low Very Low Very Low
Leukemia 4 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Carcinoma In Situ 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The comparative analyses also indicated that immortalization of epithelial cells with the E6E7 gene (HBE4 or HBE137) or constitutive activation of ERK pathway (H23) correlated with a lower growth inhibition by OSM.
HBE137 Positive_regulation (activation) of ERK in epithelial cells
1) Confidence 0.01 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.14 Pain Relevance 0.11

General Comments

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