INT188228

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 0.72
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)
Anatomy Link Frequency
epithelial cells 4
band 2
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 161 99.98 Very High Very High Very High
agonist 16 93.92 High High
Inflammation 64 91.36 High High
Inflammatory mediators 20 5.00 Very Low Very Low Very Low
tolerance 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 5 5.00 Very Low Very Low Very Low
addiction 5 5.00 Very Low Very Low Very Low
Sicca syndrome 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 85 91.36 High High
Adhesions 47 88.32 High High
Cancer 31 85.60 High High
Obesity 106 77.48 Quite High
Diabetes Mellitus 8 68.68 Quite High
Carcinoma 32 50.12 Quite High
Prostate Cancer 27 50.00 Quite Low
Necrosis 3 50.00 Quite Low
Cleidocranial Dysplasia 8 49.56 Quite Low
Metaplasia 16 49.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RUA quantification of SRP72 band showed increased phosphorylation peaking at 120 (p < 0.05, Fig. 3B).


Positive_regulation (increased) of Phosphorylation (phosphorylation) of Fig in band
1) Confidence 0.29 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2963399 Disease Relevance 0 Pain Relevance 0
Among the abnormal epithelial cells with elevated basal ERK phosphorylation (Fig. 4B), the two cell cultures from metaplastic foci in the airway were distinct because the basal ERK phosphorylation that was equivalent to the OSM-treated control culture (Fig. 5A).
Positive_regulation (elevated) of Phosphorylation (phosphorylation) of Fig in epithelial cells
2) Confidence 0.23 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.12 Pain Relevance 0.03
Among the abnormal epithelial cells with elevated basal ERK phosphorylation (Fig. 4B), the two cell cultures from metaplastic foci in the airway were distinct because the basal ERK phosphorylation that was equivalent to the OSM-treated control culture (Fig. 5A).
Positive_regulation (equivalent) of Phosphorylation (phosphorylation) of Fig in epithelial cells
3) Confidence 0.23 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1289280 Disease Relevance 0.09 Pain Relevance 0.03
induced phosphorylation of SRP72 (Fig. 3A, lanes 6–8).
Positive_regulation (induced) of Phosphorylation (phosphorylation) of Fig
4) Confidence 0.21 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2963399 Disease Relevance 0 Pain Relevance 0
However, acute stretch did cause a significant increase in FAK-Y925 phosphorylation (Fig. 5A, bottom) perhaps mimicking events that occur later in vivo during the switch to initiate labor.
Positive_regulation (increase) of Phosphorylation (phosphorylation) of Fig
5) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759504 Disease Relevance 0.22 Pain Relevance 0
Stimulation of 1° h.AoSMCs also led to rapid F-actin polymerization (Fig. 6B) and cofilin phosphorylation with optimal responses generated using 1 ?
Positive_regulation (led) of Phosphorylation (phosphorylation) of Fig
6) Confidence 0.12 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0 Pain Relevance 0.11
As expected, U0126 inhibited cytokine-induced IRS-1 serine phosphorylation (Fig. 3D and E).
Positive_regulation (induced) of Phosphorylation (phosphorylation) of Fig associated with cytokine
7) Confidence 0.05 Published 2010 Journal Diabetes Section Body Doc Link PMC2797946 Disease Relevance 0.29 Pain Relevance 0.23
The addition of DHT to C-33 cells decreased PAcP expression and increased Her2 phosphorylation (Fig. 3A).
Positive_regulation (increased) of Phosphorylation (phosphorylation) of Fig
8) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0 Pain Relevance 0

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