INT188242

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Context Info
Confidence 0.23
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.94
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CRP) extracellular region (CRP)
Anatomy Link Frequency
platelet 2
CRP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 24 91.56 High High
Inflammatory mediators 1 74.32 Quite High
Bile 3 73.16 Quite High
Inflammatory response 1 61.32 Quite High
Inflammation 24 48.24 Quite Low
adenocard 1 27.80 Quite Low
tolerance 12 27.68 Quite Low
cytokine 5 24.52 Low Low
Infliximab 65 5.00 Very Low Very Low Very Low
Adalimumab 33 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 11 98.48 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

26 97.64 Very High Very High Very High
Hypertension 9 97.08 Very High Very High Very High
Aging 12 96.48 Very High Very High Very High
Obesity 5 96.08 Very High Very High Very High
Congenital Anomalies 4 93.80 High High
Hutchinson-gilford Progeria Syndrome 7 93.76 High High
Insulin Resistance 2 92.52 High High
INFLAMMATION 48 91.56 High High
Disease 105 88.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The placebo response decreased with increasing baseline CRP levels.
Negative_regulation (decreased) of Positive_regulation (increasing) of CRP
1) Confidence 0.23 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012434 Disease Relevance 0.30 Pain Relevance 0
In the present study, searching for novel biomarkers that may associate with abnormal glucose regulation, we found that high levels of CRP and MCP-1 measured early after an acute STEMI were associated with abnormal glucose regulation diagnosed in a stable cituation.
Negative_regulation (measured) of Positive_regulation (levels) of CRP
2) Confidence 0.21 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2940874 Disease Relevance 0.44 Pain Relevance 0.14
Patients in such families also have elevated CRP levels, and lower leptin and adiponectin levels[7].
Negative_regulation (lower) of Positive_regulation (elevated) of CRP
3) Confidence 0.11 Published 2005 Journal BMC Med Genet Section Body Doc Link PMC1289285 Disease Relevance 2.43 Pain Relevance 0
Significant reductions in serum high sensitivity C-reactive protein levels have been observed with fenofibrate treatment.63,66 Fenofibrate effectively decreases serum interleu-kin-6 levels, as well as plasma platelet-activating factor acetylohydrolase, which represents a novel inflammatory marker.66,67
Negative_regulation (reductions) of Positive_regulation (sensitivity) of C-reactive protein in platelet associated with inflammatory marker
4) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2922314 Disease Relevance 0.68 Pain Relevance 0.08

General Comments

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