INT188249

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PLAT, PLG) extracellular space (PLAT, PLG) extracellular region (PLAT, PLG)
protein modification process (PLAT) plasma membrane (PLG) cytoplasm (PLAT)
Anatomy Link Frequency
chest 1
PLAT (Homo sapiens)
PLG (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 95.40 Very High Very High Very High
cva 3 91.36 High High
aspirin 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Angina 1 95.40 Very High Very High Very High
Cv General 3 Under Development 1 91.36 High High
Cancer 21 89.64 High High
Disease 7 80.16 Quite High
Metastasis 24 69.52 Quite High
Adverse Drug Reaction 38 62.68 Quite High
Stroke 5 50.32 Quite High
Skin Cancer 47 48.52 Quite Low
Death 8 46.60 Quite Low
Hypersensitivity 6 45.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fibrin is a cofactor for plasminogen activation by tPA whereas uPAR (cell membrane-anchored uPA binding protein) is a cofactor for plasminogen activation by uPA [52].
tPA Positive_regulation (activation) of plasminogen
1) Confidence 0.10 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2956083 Disease Relevance 0.38 Pain Relevance 0
Recombinant tissue plasminogen activator (tPA) or its derivatives are recommended by ACC/AHA guidelines to be used in patients who present early after onset of chest pain or symptoms and in those with previous administration of streptokinase and at low risk of intracranial hemorrhage [20].
tPA Positive_regulation (activator) of plasminogen in chest associated with angina and cva
2) Confidence 0.08 Published 2005 Journal BMC Clin Pharmacol Section Body Doc Link PMC1291362 Disease Relevance 0.48 Pain Relevance 0.14

General Comments

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