INT188310

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.77
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde4b) signal transduction (Pde4b) nucleus (Pde4b)
cytoplasm (Pde4b)
Pde4b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurobehavioral 33 100.00 Very High Very High Very High
adenocard 2 97.44 Very High Very High Very High
anesthesia 1 37.68 Quite Low
metalloproteinase 10 5.00 Very Low Very Low Very Low
imagery 5 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
5HT 2 5.00 Very Low Very Low Very Low
Clonidine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 35 78.84 Quite High
Schizophrenia 79 78.76 Quite High
Congenital Anomalies 14 77.04 Quite High
Manic Depressive Disorder 41 69.28 Quite High
Hypertension 1 67.76 Quite High
Cardiomegaly 4 59.00 Quite High
Psychosis 171 56.88 Quite High
Increased Venous Pressure Under Development 7 14.12 Low Low
Mental Disorders 25 14.04 Low Low
Affective Disorder 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DISC1 also interacts with other proteins that may mediate neurobehavioral function, including Ndel1 and PDE4B.
PDE4B Binding (interacts) of associated with neurobehavioral
1) Confidence 0.06 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2646642 Disease Relevance 0.57 Pain Relevance 0.18
Furthermore, PASMC receiving the combination of a PDE3 and a PDE4 inhibitor exhibited a significant additive or synergistic anti-mitogenic effect as compared to each PDE inhibitor used on its own.
PDE4 Binding (combination) of
2) Confidence 0.02 Published 2005 Journal Respir Res Section Body Doc Link PMC1291406 Disease Relevance 0.21 Pain Relevance 0

General Comments

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