INT188417

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.09
Pain Relevance 1.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pdxk)
Anatomy Link Frequency
muscle 1
Pdxk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 228 99.76 Very High Very High Very High
Arthritis 140 99.38 Very High Very High Very High
rheumatoid arthritis 92 97.72 Very High Very High Very High
Pain 8 89.12 High High
alcohol 4 61.92 Quite High
Inflammatory marker 12 53.52 Quite High
methotrexate 8 5.00 Very Low Very Low Very Low
anesthesia 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 244 99.76 Very High Very High Very High
Experimental Arthritis 92 99.38 Very High Very High Very High
Rheumatoid Arthritis 96 97.72 Very High Very High Very High
Arthritis 80 91.68 High High
Pain 8 89.12 High High
Disease 24 86.80 High High
Inflammatory Bowel Disease 4 73.48 Quite High
Injury 4 70.56 Quite High
Coronary Artery Disease 4 65.96 Quite High
Appetite Loss 4 65.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The objective of the present study was to determine whether inflammation directly decreases the primary pools of vitamin B6 metabolism and storage, and to examine whether inflammation alters the excretion of vitamin B6 in vivo.


Localization (excretion) of vitamin B6 associated with inflammation
1) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297572 Disease Relevance 1.37 Pain Relevance 0.58
Adjuvant arthritis was induced in rats for investigating hepatic and muscle contents as well as the urinary excretion of vitamin B6 during acute and chronic inflammation.
Localization (excretion) of vitamin B6 in muscle associated with inflammation, experimental arthritis and arthritis
2) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Abstract Doc Link PMC1297572 Disease Relevance 1.05 Pain Relevance 0.56
Adjuvant arthritis does not increase the urinary excretion of vitamin B6 at peak inflammation or during the chronic phase of inflammation
Localization (excretion) of vitamin B6 associated with inflammation, experimental arthritis and arthritis
3) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297572 Disease Relevance 0.95 Pain Relevance 0.47
To summarize these observations, the abnormal vitamin B6 status in rheumatoid arthritis results from the inflammatory process, and it is unlikely that it resulted from insufficient intake or excessive excretion of vitamin B6.


Localization (excretion) of vitamin B6 associated with inflammation and rheumatoid arthritis
4) Confidence 0.01 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297572 Disease Relevance 0.72 Pain Relevance 0.31

General Comments

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