INT188427

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pdxp) extracellular space (IL6) aging (IL6)
extracellular region (IL6) plasma membrane (Pdxp) cytoplasm (Pdxp)
Anatomy Link Frequency
plasma 1
IL6 (Homo sapiens)
Pdxp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 1 99.98 Very High Very High Very High
Inflammation 57 99.80 Very High Very High Very High
rheumatoid arthritis 23 85.76 High High
Arthritis 35 80.72 Quite High
Inflammatory marker 3 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 61 99.80 Very High Very High Very High
Cirrhosis 1 93.60 High High
Rheumatoid Arthritis 24 85.76 High High
Arthritis 20 80.72 Quite High
Disease 6 75.92 Quite High
Experimental Arthritis 23 56.96 Quite High
Myocardial Infarction 1 49.88 Quite Low
Targeted Disruption 1 36.12 Quite Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
McCarty hypothesized that the pro-inflammatory cytokine interleukin-6 might stimulate the activity of pyridoxal phosphatase in hepatocytes, in these patients, and the elevated enzyme may result in reduced plasma pyridoxal 5'-phosphate concentrations [36].
interleukin-6 Spec (might) Positive_regulation (stimulate) of pyridoxal phosphatase in plasma associated with inflammation and cytokine
1) Confidence 0.00 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297572 Disease Relevance 0.84 Pain Relevance 0.38

General Comments

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