INT188454

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (NUP62) small molecule metabolic process (NUP62) carbohydrate metabolic process (NUP62)
transmembrane transport (NUP62) cytoplasm (NUP62) nucleocytoplasmic transport (NUP62)
NUP62 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 8 45.40 Quite Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bone Disease 146 98.44 Very High Very High Very High
Congenital Anomalies 8 65.36 Quite High
Disease 26 56.72 Quite High
Osteogenic Sarcomas 20 49.48 Quite Low
Pain 8 45.40 Quite Low
Hyperplasia 2 10.16 Low Low
Cancer 8 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Osteolysis 4 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exon 8 of the p62/SQSTM1 gene was amplified by PCR (I-Cycler; Bio-Rad Laboratories, Milan, Italy) using a couple of primers located in the flanking intron: 5'-CAGTGTGGCCTGTGAGGAC-3'/5'-CAGTGAGCCTTGGGTCTCG-3'.
Positive_regulation (amplified) of p62
1) Confidence 0.36 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297578 Disease Relevance 0.21 Pain Relevance 0
Segregation of a M404V mutation of the p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget's disease of bone in an Italian family

Mutations of the p62/Sequestosome 1 gene (p62/SQSTM1) account for both sporadic and familial forms of Paget's disease of bone (PDB).

Positive_regulation (mutation) of p62 associated with bone disease
2) Confidence 0.17 Published 2005 Journal Arthritis Res Ther Section Title Doc Link PMC1297578 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox