INT188456

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (NUP62) small molecule metabolic process (NUP62) carbohydrate metabolic process (NUP62)
transmembrane transport (NUP62) cytoplasm (NUP62) nucleocytoplasmic transport (NUP62)
NUP62 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 1 95.36 Very High Very High Very High
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 4 99.08 Very High Very High Very High
Necrosis 2 98.80 Very High Very High Very High
Bone Disease 73 97.54 Very High Very High Very High
Hypercalcemia 1 78.60 Quite High
Metabolic Bone Disease 1 76.80 Quite High
Disease 13 25.04 Quite Low
Osteogenic Sarcomas 10 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Osteolysis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations of the p62/sequestosome 1 (p62/SQSTM1) gene account for most of the sporadic and familial forms of PDB [1-5], and exons 7 and 8, encoding the ubiquitin-binding-associated domain (UBA), host a clustered mutational area [2-5]. p62 acts as a scaffold protein in signalling pathways downstream of the interleukin-1, tumour necrosis factor (TNF)-?
Negative_regulation (downstream) of Gene_expression (pathways) of p62 associated with necrosis, cancer and bone disease
1) Confidence 0.33 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297578 Disease Relevance 0.99 Pain Relevance 0.05

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox