INT188511

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.22
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) nucleus (Ppara) DNA binding (Ppara)
Ppara (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 21 85.96 High High
Potency 16 85.24 High High
Inflammatory mediators 1 78.72 Quite High
Inflammation 25 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 4 79.48 Quite High
INFLAMMATION 30 78.32 Quite High
Arthritis 3 62.80 Quite High
Osteoarthritis 2 30.36 Quite Low
Stress 7 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RT–PCR analysis comparing Srebp-1c, Ppard, Ppara, Ins (proinsulin), Ucp-2, Ampk and Gck mRNA expression in BRIN-BD11 cells treated in the absence or presence of increasing concentrations of AA for 24 h was performed.
Positive_regulation (comparing) of Transcription (expression) of Ppara
1) Confidence 0.22 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2990202 Disease Relevance 0 Pain Relevance 0
Finally, one could underline that the contribution of PPAR?
Positive_regulation (underline) of Transcription (contribution) of PPAR
2) Confidence 0.18 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297580 Disease Relevance 0.22 Pain Relevance 0.26

General Comments

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