INT188513

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.02
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) nucleus (Ppara) DNA binding (Ppara)
Ppara (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 28 98.68 Very High Very High Very High
cINOD 9 94.80 High High
agonist 34 92.40 High High
Arthritis 1 81.92 Quite High
Inflammatory stimuli 2 78.08 Quite High
cytokine 3 66.48 Quite High
Potency 16 20.00 Low Low
corticosteroid 1 15.56 Low Low
antagonist 5 8.56 Low Low
ischemia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 34 98.68 Very High Very High Very High
Apoptosis 56 96.20 Very High Very High Very High
Colon Cancer 2 95.60 Very High Very High Very High
Experimental Arthritis 1 81.92 Quite High
Cancer 5 81.40 Quite High
Death 8 77.92 Quite High
Necrosis 1 67.16 Quite High
Stress 6 36.72 Quite Low
Hypoxia 6 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results from our laboratories have shown that sulindac sulfide and indomethacin suppress PPAR?
Negative_regulation (suppress) of PPAR Binding (indomethacin) of
1) Confidence 0.35 Published 2010 Journal PPAR Research Section Body Doc Link PMC2938460 Disease Relevance 1.26 Pain Relevance 0.53
However, COX-2 represents only the first inducible step in the stimulated synthesis of PG [12] and its inhibition by PPAR?
Negative_regulation (represents) of PPAR Neg (inhibition) Binding (inhibition) of
2) Confidence 0.15 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297580 Disease Relevance 0.76 Pain Relevance 0.49

General Comments

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