INT188521

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90aa1, Ptges3) protein complex (Hsp90aa1, Ptges3) cytoplasm (Hsp90aa1, Ptges3)
isomerase activity (Ptges3) intracellular (Hsp90aa1) cell proliferation (Ptges3)
Hsp90aa1 (Rattus norvegicus)
Ptges3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 23 88.40 High High
cytokine 3 75.36 Quite High
corticosteroid 1 66.64 Quite High
Inflammatory stimuli 2 53.24 Quite High
agonist 21 50.00 Quite Low
cINOD 2 46.20 Quite Low
Potency 16 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 1 100.00 Very High Very High Very High
INFLAMMATION 28 88.40 High High
Arthritis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One of its isoforms, cPGES-1, is a cytosolic protein found as a complex with heat shock protein 90 (Hsp90) that is constitutively expressed in a wide variety of cells and tissues.
Hsp90 Binding (complex) of cPGES-1 associated with shock
1) Confidence 0.02 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297580 Disease Relevance 0.61 Pain Relevance 0.33

General Comments

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