INT188580

Context Info Confidence 0.21 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.26 Pain Relevance 0.26

extracellular space (CD14) extracellular region (CD14) plasma membrane (CD14)

Anatomy Link Frequency T cells 2 CD14 (Homo sapiens)

Pain Link Frequency Relevance Heat spinal inflammation 31 90.36 rheumatoid arthritis 20 19.56 Arthritis 16 19.20 cytokine 5 5.00 Inflammation 2 5.00 tolerance 1 5.00 Infliximab 1 5.00

Disease Link Frequency Relevance Heat Low Back Pain 31 90.36 Rheumatoid Arthritis 20 19.56 Seronegative Spondarthritis 16 19.20 Disease 8 5.00 Necrosis 4 5.00 Cancer 4 5.00 INFLAMMATION 2 5.00 Sprains And Strains 1 5.00 Syndrome 1 5.00 Body Weight 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To investigate whether sCD14 from autologous serum was crucial for a stronger response of CD4+CD28null T cells to LPS, cells were incubated with a blocking antibody directed against CD14 prior to the addition of LPS.

Negative_regulation (blocking) of Positive_regulation (directed) of CD14 in T cells

1) Confidence 0.21 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1297589 Disease Relevance 0.26 Pain Relevance 0.26

General Comments

This test has worked.