INT188632

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Context Info
Confidence 0.16
First Reported 2005
Last Reported 2007
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.13
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 1
Sig (Mus musculus)
Pain Link Frequency Relevance Heat
cva 18 96.00 Very High Very High Very High
alcohol 15 5.00 Very Low Very Low Very Low
iatrogenic 8 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhagic Shock 51 99.00 Very High Very High Very High
Acid Base Imbalance 147 98.08 Very High Very High Very High
Shock 130 97.98 Very High Very High Very High
Hemorrhage 18 96.00 Very High Very High Very High
Acidosis 68 94.00 High High
Vasculitis 8 79.76 Quite High
Critical Illness 57 78.60 Quite High
Injury 11 77.60 Quite High
Malaria 6 75.76 Quite High
Congenital Anomalies 22 74.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Despite a slight increase in sulfate after induction of shock, changes in serum concentration of sulfate were small throughout the experiment and, thus, were not responsible for the observed changes in AG and SIG.
Neg (not) Regulation (responsible) of SIG associated with shock
1) Confidence 0.16 Published 2007 Journal Crit Care Section Body Doc Link PMC2246228 Disease Relevance 0.73 Pain Relevance 0.05
However, others simply reported absolute values of SID, SIG, chloride, anion gap, and SBE in association with mortality prediction rather than attempting to classify various subtypes of metabolic acidosis [15,20,24].
Regulation (values) of SIG associated with acid base imbalance
2) Confidence 0.14 Published 2005 Journal Crit Care Section Body Doc Link PMC1297622 Disease Relevance 0.69 Pain Relevance 0
This may be related to the technology used to measure acid–base variables [72-74] or administration of medications or fluid (e.g. gelatins) [25,26] that alter the SIG.
Regulation (alter) of SIG
3) Confidence 0.14 Published 2005 Journal Crit Care Section Body Doc Link PMC1297622 Disease Relevance 0.56 Pain Relevance 0
Fluid resuscitation might have affected the SIG in the present model of hemorrhagic shock, although only hydroxyethyl starch solutions were given.
Spec (might) Regulation (affected) of SIG associated with hemorrhagic shock
4) Confidence 0.09 Published 2007 Journal Crit Care Section Body Doc Link PMC2246228 Disease Relevance 0.66 Pain Relevance 0
Since citrate changes in serum are a balance between endogenous production, exogenous load, and liver metabolism, a contribution of exogenous citrate to the changes in SIG cannot be ruled out totally.
Regulation (changes) of SIG in liver
5) Confidence 0.09 Published 2007 Journal Crit Care Section Body Doc Link PMC2246228 Disease Relevance 0.50 Pain Relevance 0

General Comments

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