INT188687

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Spg7) mitochondrion (Spg7) cell adhesion (Spg7)
mitochondrion organization (Spg7)
Spg7 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 5 98.12 Very High Very High Very High
cytokine 32 97.84 Very High Very High Very High
Inflammation 29 97.20 Very High Very High Very High
agonist 1 86.88 High High
Inflammatory response 2 56.40 Quite High
Central nervous system 18 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 97.20 Very High Very High Very High
Drug Induced Neurotoxicity 1 77.84 Quite High
Injury 6 48.08 Quite Low
Alzheimer's Dementia 32 5.00 Very Low Very Low Very Low
Multiple Sclerosis 16 5.00 Very Low Very Low Very Low
Demyelinating Disease 9 5.00 Very Low Very Low Very Low
Amyloid Plaque 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Encephalitis 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Those authors found that the effect of PGN was critically dependent on TLR2, as TLR2-deficient mice demonstrated reduced cytokine and chemokine production after PGN challenge [34].
Negative_regulation (dependent) of Negative_regulation (effect) of PGN associated with chemokine and cytokine
1) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1298325 Disease Relevance 0.31 Pain Relevance 0.40

General Comments

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