INT188694

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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Traf6, Irf3) nucleus (Traf6, Irf3) DNA binding (Irf3)
protein complex assembly (Traf6) protein complex (Traf6) ligase activity (Traf6)
Traf6 (Mus musculus)
Irf3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 32 94.56 High High
Inflammation 29 77.96 Quite High
Multiple sclerosis 4 38.96 Quite Low
Central nervous system 18 32.80 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 77.96 Quite High
Demyelinating Disease 9 53.76 Quite High
Encephalitis 4 49.36 Quite Low
Multiple Sclerosis 16 45.84 Quite Low
Disease 7 39.60 Quite Low
Autoimmune Disease 1 36.72 Quite Low
Sprains And Strains 2 25.36 Quite Low
Alzheimer's Dementia 32 5.00 Very Low Very Low Very Low
Amyloid Plaque 7 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These adapter molecules bind to the intracellular leucine-rich repeat region of the TLR and promote recruitment of additional factors such as IRAKs and TRAF6 that allow for activation of transcription factors including IRF-3 and NF-?
TRAF6 Positive_regulation (allow) of Positive_regulation (activation) of IRF-3
1) Confidence 0.08 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1298325 Disease Relevance 0.20 Pain Relevance 0.15

General Comments

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