INT188696

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cd40) extracellular region (Cd40) plasma membrane (Cd40)
enzyme binding (Cd40)
Anatomy Link Frequency
bone marrow 2
Cd40 (Mus musculus)
Eae1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 64 95.28 Very High Very High Very High
Multiple sclerosis 8 58.48 Quite High
Nerve growth factor 2 48.52 Quite Low
Inflammation 58 44.08 Quite Low
Central nervous system 36 27.04 Quite Low
chemokine 10 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 32 100.00 Very High Very High Very High
Disease 14 84.64 Quite High
Demyelinating Disease 18 62.60 Quite High
INFLAMMATION 56 44.08 Quite Low
Death 2 9.24 Low Low
Paralysis 4 7.68 Low Low
Alzheimer's Dementia 64 5.00 Very Low Very Low Very Low
Amyloid Plaque 14 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low
Encephalitis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In an effort to further understand the nature of the CD40-CD40L interaction responsible for promotion of EAE, Becher and colleagues used a bone marrow reconstitution system to determine which CD40-expressing cells were responsible for promoting EAE [57].
CD40 Binding (interaction) of EAE in bone marrow associated with multiple sclerosis
1) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1298325 Disease Relevance 0.78 Pain Relevance 0.10
In an effort to further understand the nature of the CD40-CD40L interaction responsible for promotion of EAE, Becher and colleagues used a bone marrow reconstitution system to determine which CD40-expressing cells were responsible for promoting EAE [57].
CD40 Binding (interaction) of EAE in bone marrow associated with multiple sclerosis
2) Confidence 0.05 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1298325 Disease Relevance 0.78 Pain Relevance 0.10

General Comments

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