INT188734

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Context Info
Confidence 0.52
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Egfr, EGFR) nucleus (Egfr, EGFR) endosome (Egfr, EGFR)
cell morphogenesis (Egfr, EGFR) endoplasmic reticulum (Egfr, EGFR) Golgi apparatus (Egfr, EGFR)
Egfr (Mus musculus)
EGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 1 38.80 Quite Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 3 98.20 Very High Very High Very High
Disease 9 92.60 High High
Neuroepithelial Neoplasms 9 91.12 High High
Cancer 23 77.04 Quite High
Glioblastoma 22 50.00 Quite Low
Necrosis 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Central Nervous System Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EGFR and EGFRvIII expression have been shown to increase the infiltrative and invasive properties of glioma cells [24,25], therefore, one could hypothesize that patients expressing these markers may be more likely to present with multifocal disease, ependymal dissemination, or gliomatosis cerebri and perhaps this is the confounding variable between the studies accounting for the discrepancy in prognostic impact.
EGFR Positive_regulation (increase) of Gene_expression (expression) of EGFR associated with neuroepithelial neoplasms, disease and glioma
1) Confidence 0.52 Published 2005 Journal J Transl Med Section Body Doc Link PMC1298339 Disease Relevance 0.61 Pain Relevance 0

General Comments

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