INT188801

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Tnfsf11) extracellular region (Il6, Tnfsf11) cell differentiation (Tnfsf11)
plasma membrane (Tnfsf11) intracellular (Tnfsf11) cytoplasm (Tnfsf11)
Il6 (Mus musculus)
Tnfsf11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 20 98.92 Very High Very High Very High
Inflammatory mediators 1 72.56 Quite High
Inflammation 36 50.00 Quite Low
withdrawal 1 33.44 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 8 99.92 Very High Very High Very High
Osteoporosis 46 99.84 Very High Very High Very High
INFLAMMATION 36 72.16 Quite High
Lifespan 2 57.36 Quite High
Apoptosis 4 53.12 Quite High
Autoimmune Disease 2 43.12 Quite Low
Postmenopausal Osteoporosis 3 32.24 Quite Low
Necrosis 2 5.56 Low Low
Cancer 4 5.20 Low Low
Aging 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-6 contributes to RANKL upregulation in osteoblastic cells.
IL-6 Positive_regulation (contributes) of Positive_regulation (upregulation) of RANKL associated with osteoporosis
1) Confidence 0.06 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1308846 Disease Relevance 0.46 Pain Relevance 0.21

General Comments

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