INT188804

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100a8, Tnfsf11) extracellular region (S100a8, Tnfsf11) plasma membrane (S100a8, Tnfsf11)
cytoplasm (S100a8, Tnfsf11) cell differentiation (Tnfsf11) intracellular (Tnfsf11)
Anatomy Link Frequency
osteoblasts 2
S100a8 (Mus musculus)
Tnfsf11 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 36 100.00 Very High Very High Very High
cytokine 20 100.00 Very High Very High Very High
Inflammatory mediators 1 39.48 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 100.00 Very High Very High Very High
Autoimmune Disease 2 99.30 Very High Very High Very High
Apoptosis 4 92.24 High High
Lifespan 2 90.08 High High
Osteoporosis 46 79.16 Quite High
Hypercalcemia 8 66.84 Quite High
Aging 14 47.52 Quite Low
Disease 13 28.72 Quite Low
Atherosclerosis 3 23.60 Low Low
Asthma 1 20.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In inflammatory or autoimmune disease states, activated T cells produce RANKL and pro-inflammatory cytokines, all of which can induce RANKL expression in osteoblasts [40].
pro-inflammatory Positive_regulation (induce) of Gene_expression (expression) of RANKL in osteoblasts associated with autoimmune disease, inflammation and cytokine
1) Confidence 0.00 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1308846 Disease Relevance 0.70 Pain Relevance 0.31

General Comments

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