INT188805

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Context Info
Confidence 0.15
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.96
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TNF, Crp) signal transduction (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
liver 2
TNF (Homo sapiens)
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 20 97.60 Very High Very High Very High
Inflammation 36 95.68 Very High Very High Very High
Arthritis 1 87.88 High High
spinal inflammation 1 86.88 High High
rheumatoid arthritis 7 85.92 High High
metalloproteinase 1 54.80 Quite High
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 8 98.80 Very High Very High Very High
INFLAMMATION 36 95.68 Very High Very High Very High
Necrosis 2 92.32 High High
Cancer 4 91.96 High High
Osteoporosis 46 90.92 High High
Seronegative Spondarthritis 1 87.88 High High
Low Back Pain 1 86.88 High High
Rheumatoid Arthritis 7 85.92 High High
Osteomyelitis 1 85.04 High High
Crystal Associated Disease 1 84.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
C-reactive protein (CRP) production in the liver is upregulated by IL-1, IL-6 and TNF-?
TNF Positive_regulation (upregulated) of Gene_expression (production) of CRP in liver
1) Confidence 0.15 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1308846 Disease Relevance 2.96 Pain Relevance 0.95

General Comments

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