INT188844

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Context Info
Confidence 0.58
First Reported 2005
Last Reported 2011
Negated 5
Speculated 3
Reported most in Body
Documents 44
Total Number 47
Disease Relevance 33.94
Pain Relevance 5.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AES)
Anatomy Link Frequency
Monocyte 2
thyroid 2
arm 1
reproductive tract 1
neutrophil 1
AES (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 211 100.00 Very High Very High Very High
abdominal pain 7 100.00 Very High Very High Very High
cINOD 95 99.60 Very High Very High Very High
pruritus 15 98.64 Very High Very High Very High
headache 114 98.48 Very High Very High Very High
Osteoarthritis 18 98.32 Very High Very High Very High
methotrexate 47 98.22 Very High Very High Very High
Migraine 51 97.08 Very High Very High Very High
nud 8 96.64 Very High Very High Very High
cva 15 94.44 High High
Disease Link Frequency Relevance Heat
Arthropathy 485 100.00 Very High Very High Very High
Pain 226 100.00 Very High Very High Very High
Vomiting 103 100.00 Very High Very High Very High
Diarrhoea 32 100.00 Very High Very High Very High
Hypoglycemia 21 100.00 Very High Very High Very High
Sinusitis 14 100.00 Very High Very High Very High
Myalgia 13 100.00 Very High Very High Very High
Asthenia 8 100.00 Very High Very High Very High
Abdominal Pain 7 100.00 Very High Very High Very High
Anorexia 3 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two hundred and ten patients (23.1%) experienced AEs, without statistically significant differences in incidence emerging between the placebo (21.6%) and the treatment groups (21.1%, 6.25 mg; 25.7%, 12.5 mg).
Neg (without) Gene_expression (experienced) of AEs
1) Confidence 0.58 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656322 Disease Relevance 1.45 Pain Relevance 0.47
Reducing these nuisance AEs can lead to increased tolerability, compliance and patient satisfaction.
Gene_expression (Reducing) of AEs
2) Confidence 0.58 Published 2010 Journal International Journal of Clinical Practice Section Body Doc Link PMC2984542 Disease Relevance 0.25 Pain Relevance 0.99
Arthropathy AEs appeared to be less likely to occur in patients who had a good clinical response to treatment (?
Gene_expression (appeared) of AEs associated with arthropathy
3) Confidence 0.57 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 1.26 Pain Relevance 0
Arthropathy AEs appeared to be less likely to occur in patients who had a good clinical response to treatment (?
Gene_expression (Arthropathy) of AEs associated with arthropathy
4) Confidence 0.57 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 1.27 Pain Relevance 0
Arthropathy AEs appeared to be less likely to occur in patients who had a good clinical response to treatment (?
Spec (likely) Gene_expression (likely) of AEs associated with arthropathy
5) Confidence 0.57 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 1.26 Pain Relevance 0
There were no differences in baseline demographics or disease characteristics between the patients who had arthropathy AEs and those who did not.
Gene_expression (had) of AEs associated with arthropathy and disease
6) Confidence 0.57 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 1.21 Pain Relevance 0
However, the proportion of AEs that were moderate or severe was greater in the efalizumab groups than in the placebo groups; too few patients had events to draw any meaningful conclusions.
Gene_expression (proportion) of AEs
7) Confidence 0.57 Published 2006 Journal Arch Dermatol Res Section Body Doc Link PMC1705535 Disease Relevance 0.62 Pain Relevance 0
The AEs resolved in three of these four patients.
Gene_expression (resolved) of AEs
8) Confidence 0.57 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833973 Disease Relevance 1.92 Pain Relevance 0.10
Following resolution of the AEs, the infusion was to be resumed at half the previous rate.
Gene_expression (resolution) of AEs
9) Confidence 0.57 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833973 Disease Relevance 0.59 Pain Relevance 0.09
Primary outcome measures were AEs occurring during the in-hospital stay of patients undergoing primary THR.
Gene_expression (occurring) of AEs
10) Confidence 0.56 Published 2009 Journal Patient Saf Surg Section Body Doc Link PMC2674031 Disease Relevance 0.73 Pain Relevance 0.12
All AEs were generic and not related to the material.
Neg (not) Gene_expression (generic) of AEs
11) Confidence 0.53 Published 2010 Journal Int Urogynecol J Section Body Doc Link PMC2977052 Disease Relevance 0.49 Pain Relevance 0.08
AEs were experienced by 26/30 (87%) subjects.
Gene_expression (experienced) of AEs
12) Confidence 0.52 Published 2010 Journal BMC Clin Pharmacol Section Body Doc Link PMC2987775 Disease Relevance 0.33 Pain Relevance 0.20
However, more participants in the SAVVY group had reproductive tract AEs, with an incidence of 14.5 per 100 person-years in the SAVVY group versus 10.9 per 100 person-years in the in the placebo group (rate ratio?
Gene_expression (had) of AEs in reproductive tract
13) Confidence 0.49 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2129116 Disease Relevance 1.17 Pain Relevance 0.36
Discontinuation because of AEs occurred more often with dapoxetine 60 mg than with dapoxetine 30 mg.61,63,64,69
Gene_expression (occurred) of AEs
14) Confidence 0.45 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695237 Disease Relevance 0.68 Pain Relevance 0.11
T-tests were used to examine differences in the age, age at diagnosis, severity (HAQ index and SJC), the dose of MTX, and the duration of disease between the patients with AEs or SAEs and the patients who had no AEs or SAEs.
Neg (no) Gene_expression (had) of AEs associated with disease and methotrexate
15) Confidence 0.43 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911915 Disease Relevance 0.43 Pain Relevance 0.17
Otherwise, we did not identify significant risk factors for AEs overall, SAEs, infections, or IRs in this study.
Gene_expression (overall) of AEs associated with infection
16) Confidence 0.43 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911915 Disease Relevance 0.83 Pain Relevance 0.21
The most frequently reported AEs were low hemoglobin count (<8 g/dL; n=161, 13.3%), low neutrophil count (<1.0x109/L associated with fever of ?
Gene_expression (count) of AEs in neutrophil associated with fever
17) Confidence 0.42 Published 2011 Journal Journal of Cancer Section Body Doc Link PMC3020361 Disease Relevance 1.04 Pain Relevance 0
None of the AEs was classified as serious.
Neg (None) Gene_expression (None) of AEs
18) Confidence 0.40 Published 2010 Journal Acta Paediatrica (Oslo, Norway : 1992) Section Body Doc Link PMC2855831 Disease Relevance 0.09 Pain Relevance 0
The most prevalent AEs (i.e., ?
Gene_expression (prevalent) of AEs
19) Confidence 0.38 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC3017894 Disease Relevance 0.98 Pain Relevance 0.19
The most commonly observed AEs occurring in ?
Gene_expression (occurring) of AEs
20) Confidence 0.30 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656329 Disease Relevance 0.81 Pain Relevance 0.16

General Comments

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