INT188851

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde2a) signal transduction (Pde2a) Golgi apparatus (Pde2a)
endoplasmic reticulum (Pde2a) plasma membrane (Pde2a) nucleus (Pde2a)
Anatomy Link Frequency
spinal cord 2
Pde2a (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 58 99.74 Very High Very High Very High
Morphine 32 98.44 Very High Very High Very High
Eae 12 95.68 Very High Very High Very High
analgesia 4 85.44 High High
Pain 22 79.20 Quite High
Analgesic 6 78.64 Quite High
allodynia 20 71.52 Quite High
withdrawal 8 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 8 95.68 Very High Very High Very High
Sprains And Strains 8 90.16 High High
Nociception 50 85.32 High High
Pain 26 79.20 Quite High
Neuropathic Pain 22 71.52 Quite High
INFLAMMATION 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our morphine data were particularly helpful in understanding the mechanisms governing the control of expression of the CO/NO-cGMP system genes and the consequences of the enhanced expression.
Regulation (control) of Gene_expression (expression) of cGMP associated with morphine
1) Confidence 0.04 Published 2005 Journal Mol Pain Section Body Doc Link PMC1310513 Disease Relevance 0.22 Pain Relevance 0.33
However, our observations do support the hypothesis that within the spinal cord multi-level changes in CO/NO-cGMP system gene expression follow noxious stimulation.
Regulation (changes) of Gene_expression (expression) of cGMP in spinal cord associated with spinal cord
2) Confidence 0.04 Published 2005 Journal Mol Pain Section Body Doc Link PMC1310513 Disease Relevance 0.54 Pain Relevance 0.61

General Comments

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