INT189017

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Context Info
Confidence 0.14
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pax3, Lmna) cell proliferation (Pax3) nuclear envelope (Lmna)
structural molecule activity (Lmna) DNA binding (Pax3) cytoplasm (Lmna)
Anatomy Link Frequency
inhibitory interneurons 1
Pax3 (Mus musculus)
Lmna (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 87 100.00 Very High Very High Very High
Pain 20 95.36 Very High Very High Very High
projection neuron 3 94.72 High High
Glutamate 20 91.24 High High
potassium channel 1 91.24 High High
gABA 3 89.40 High High
Action potential 3 81.88 Quite High
primary afferent fibers 8 80.88 Quite High
GABAergic 4 78.76 Quite High
Analgesic 5 50.00 Quite Low
Disease Link Frequency Relevance Heat
Bordatella Infection 2 99.96 Very High Very High Very High
Pain 16 95.36 Very High Very High Very High
Targeted Disruption 2 59.80 Quite High
Sprains And Strains 1 59.24 Quite High
Nociception 11 54.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In lamina V, SP binds pertussis toxin-sensitive Gi/Go-coupled NK1R on inhibitory interneurons, which leads to a cascade of downstream events that may result in changes in the activity of non-selective cation channels or inwardly rectifying potassium channels [12] ultimately leading to GABA and/or glycine release.
SP Binding (binds) of lamina in inhibitory interneurons associated with gaba, bordatella infection, potassium channel and substance p
1) Confidence 0.14 Published 2005 Journal Mol Pain Section Body Doc Link PMC1315348 Disease Relevance 0.42 Pain Relevance 1.16

General Comments

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