INT189103

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Tap1, Tap2) endoplasmic reticulum (Tap1, Tap2) ATPase activity (Tap1, Tap2)
plasma membrane (Tap1, Tap2) transmembrane transport (Tap1, Tap2) mitochondrion (Tap1)
Tap1 (Mus musculus)
Tap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 38 84.64 Quite High
Viral Infection 10 31.72 Quite Low
Pox Virus Infection 30 5.00 Very Low Very Low Very Low
Sprains And Strains 16 5.00 Very Low Very Low Very Low
Vesicular Stomatitis 8 5.00 Very Low Very Low Very Low
Weight Loss 6 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Communicable Diseases 4 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 5.00 Very Low Very Low Very Low
Immunization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These genes include (1) the proteasome components, low molecular-weight polypeptides (LMPs): LMP2, LMP7, and LMP10; (2) transporters associated with antigen processing (TAP): TAP1 and TAP2; (3) the chaperone proteins: calnexin, calreticulin, and tapasin; and (4) MHC class I heavy chain and ?
TAP1 Binding (associated) of TAP2
1) Confidence 0.21 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0.08 Pain Relevance 0
This would imply that when mouse TAP1 or TAP2 associates with its human TAP counterpart, they play a dominant role in selecting the peptides for transport.
TAP Binding (associates) of TAP2
2) Confidence 0.18 Published 2005 Journal PLoS Pathogens Section Body Doc Link PMC1323471 Disease Relevance 0 Pain Relevance 0

General Comments

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