INT18922

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Context Info
Confidence 0.18
First Reported 1991
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.44
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Klk1c7)
Anatomy Link Frequency
leukocyte 1
cauda epididymis 1
central nervous system 1
Klk1c7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 9 99.98 Very High Very High Very High
Central nervous system 1 99.68 Very High Very High Very High
Demyelination 2 92.24 High High
Neuritis 6 89.36 High High
ischemia 54 77.20 Quite High
metalloproteinase 30 5.00 Very Low Very Low Very Low
Inflammation 18 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reperfusion Injury 194 98.46 Very High Very High Very High
Demyelinating Disease 2 92.24 High High
Optic Neuritis 6 89.84 High High
Cv Unclassified Under Development 50 77.20 Quite High
Hypersensitivity 10 59.80 Quite High
Lung Injury 12 50.00 Quite Low
Heart Rate Under Development 18 19.84 Low Low
Injury 18 12.64 Low Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Adult Respiratory Distress Syndrome 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate the EK-producing activity of lysosomal proteinase, and also indicate the usefulness of the two substances as substrates for the enzyme.
Gene_expression (producing) of lysosomal proteinase associated with enkephalin
1) Confidence 0.18 Published 1991 Journal Life Sci. Section Abstract Doc Link 1990237 Disease Relevance 0 Pain Relevance 0.59
Calcium activated neutral proteinase (calpain) is an endopeptidase present in the central nervous system which degrades myelin proteins.
Gene_expression (present) of proteinase in central nervous system associated with central nervous system
2) Confidence 0.15 Published 1999 Journal Histol. Histopathol. Section Abstract Doc Link 10212825 Disease Relevance 0.48 Pain Relevance 0.45
Here we report that HongrES1, a new member of the SERPIN (serine proteinase inhibitor) family exclusively expressed in the rat cauda epididymis and up-regulated by androgen, is secreted into the lumen and covers the sperm head.
Gene_expression (expressed) of proteinase in cauda epididymis
3) Confidence 0.06 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2606034 Disease Relevance 0 Pain Relevance 0
Therefore, we have investigated a broad spectrum of LIRI parameters, including lung function, capillary permeability, matrix metallo proteinase (MMP) production, surfactant conversion, and histological changes on the short (days) and long-term (months) after LIRI and we have described leukocyte kinetics.
Gene_expression (production) of proteinase in leukocyte associated with reperfusion injury
4) Confidence 0.05 Published 2008 Journal Respir Res Section Body Doc Link PMC2335107 Disease Relevance 0.79 Pain Relevance 0.14
Determination of matrix-metallo-proteinase activity
Gene_expression (activity) of proteinase
5) Confidence 0.05 Published 2008 Journal Respir Res Section Body Doc Link PMC2335107 Disease Relevance 0.17 Pain Relevance 0

General Comments

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