INT189229

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Context Info
Confidence 0.20
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CHGB)
Anatomy Link Frequency
cortex 1
CHGB (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 48 5.00 Very Low Very Low Very Low
Central nervous system 32 5.00 Very Low Very Low Very Low
Pain 24 5.00 Very Low Very Low Very Low
cva 10 5.00 Very Low Very Low Very Low
spastic colon 10 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Pain threshold 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 28 99.76 Very High Very High Very High
Alzheimer's Dementia 28 94.00 High High
Disorder Of Lipid Metabolism 10 92.96 High High
Syndrome 78 91.04 High High
Cerebral Amyloid Angiopathy 22 90.64 High High
Amyloidosis 18 85.56 High High
Chronic Fatigue Syndrome 368 81.12 Quite High
Creutzfeldt Jakob Disease 2 73.08 Quite High
Amyloid Plaque 2 38.28 Quite Low
Sleep Disorders 48 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was a significant loss of chromogranin B – immunoreactivity in the dorsolateral, the entorhinal, and orbitofrontal cortex in Alzheimer's disease.
Negative_regulation (loss) of chromogranin B in cortex associated with disease
1) Confidence 0.20 Published 2005 Journal BMC Neurol Section Body Doc Link PMC1326206 Disease Relevance 1.54 Pain Relevance 0
The absence of chromogranin B in these anatomical locations could result in defective synaptic function and the loss of neurohormonal effects.
Negative_regulation (absence) of chromogranin B
2) Confidence 0.15 Published 2005 Journal BMC Neurol Section Body Doc Link PMC1326206 Disease Relevance 1.50 Pain Relevance 0

General Comments

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