INT189240

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Context Info
Confidence 0.23
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ORM2) extracellular space (ORM2) extracellular region (ORM2)
Anatomy Link Frequency
plasma 2
ORM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 16 97.52 Very High Very High Very High
Inflammation 14 93.32 High High
Bioavailability 6 83.28 Quite High
antagonist 3 80.36 Quite High
Bile 1 66.84 Quite High
alcohol 1 56.44 Quite High
fibrosis 10 21.12 Low Low
corticosteroid 37 20.72 Low Low
Fibrositis 24 5.00 Very Low Very Low Very Low
cytokine 19 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 1 95.28 Very High Very High Very High
INFLAMMATION 14 93.32 High High
Organ Transplantation 5 84.88 Quite High
Chronic Fatigue Syndrome 184 82.96 Quite High
Brain Injury 3 81.84 Quite High
Bacterial Respiratory Disease 1 62.64 Quite High
Disorder Of Lipid Metabolism 5 57.28 Quite High
Apoptosis 5 40.64 Quite Low
Renal Failure 11 37.92 Quite Low
Cirrhosis 8 23.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ORM2 is a glycosylated plasma lipocalin with a hydrophobic pocket that binds a wide variety of drugs, hemin, progesterone and the CCR5 receptor on macrophage – lineage cells [57,58].
ORM2 Binding (binds) of in plasma
1) Confidence 0.23 Published 2005 Journal BMC Neurol Section Body Doc Link PMC1326206 Disease Relevance 0.57 Pain Relevance 0.21
Sirolimus is extensively bound to plasma proteins (92%), particularly albumin, alpha-one acid glycoprotein, and lipoproteins.
alpha-one acid glycoprotein Binding (bound) of in plasma
2) Confidence 0.01 Published 2009 Journal Journal of Transplantation Section Body Doc Link PMC2809333 Disease Relevance 0.18 Pain Relevance 0.10

General Comments

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