INT1893

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.79
First Reported 1975
Last Reported 2010
Negated 2
Speculated 5
Reported most in Abstract
Documents 1041
Total Number 1051
Disease Relevance 340.23
Pain Relevance 256.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gh) signal transduction (Gh) mitochondrion (Gh)
extracellular space (Gh) extracellular region (Gh) plasma membrane (Gh)
Anatomy Link Frequency
pituitary 121
plasma 31
body 25
anterior pituitary 16
thyroid 10
Gh (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 3203 100.00 Very High Very High Very High
Clonidine 2090 100.00 Very High Very High Very High
narcan 406 100.00 Very High Very High Very High
noradrenaline 84 100.00 Very High Very High Very High
Sumatriptan 364 99.92 Very High Very High Very High
dexamethasone 174 99.92 Very High Very High Very High
Pain 167 99.92 Very High Very High Very High
opiate 140 99.92 Very High Very High Very High
Glutamate 72 99.90 Very High Very High Very High
depression 198 99.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 3337 100.00 Very High Very High Very High
Acromegaly 2647 100.00 Very High Very High Very High
Obesity 1745 100.00 Very High Very High Very High
Adenoma 1086 100.00 Very High Very High Very High
Reprotox - General 1 206 100.00 Very High Very High Very High
Galactorrhea 185 100.00 Very High Very High Very High
Growth Hormone Deficiency 150 100.00 Very High Very High Very High
Prolactinoma 125 100.00 Very High Very High Very High
Gigantism 53 100.00 Very High Very High Very High
Coagulation Disorder 4 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The level of GH secretion induced by clonidine was significantly reduced after ECT, but the hypotensive responses to clonidine remained unchanged.
Localization (secretion) of GH associated with hypotension and clonidine
1) Confidence 0.79 Published 1992 Journal Psychiatry Res Section Abstract Doc Link 1317592 Disease Relevance 0.19 Pain Relevance 0.29
The authors give an account of their five-year experience with the clonidine test of growth hormone (GH) secretion.
Localization (secretion) of GH associated with clonidine
2) Confidence 0.79 Published 1991 Journal Cesk Pediatr Section Abstract Doc Link 1806268 Disease Relevance 0 Pain Relevance 0.27
The test is a very useful screening examination of GH secretion due to the useful information it provides, and because it is simple and safe even when used in ambulatory practice.
Localization (secretion) of GH
3) Confidence 0.79 Published 1991 Journal Cesk Pediatr Section Abstract Doc Link 1806268 Disease Relevance 0 Pain Relevance 0.24
The authors give an account of their five-year experience with the clonidine test of growth hormone (GH) secretion.
Localization (secretion) of growth hormone associated with clonidine
4) Confidence 0.79 Published 1991 Journal Cesk Pediatr Section Abstract Doc Link 1806268 Disease Relevance 0 Pain Relevance 0.27
Patients treated with fluoxetine showed a significant decrease in DMI-mediated GH release irrespective of therapeutic outcome.
Localization (release) of GH associated with desipramine and fluoxetine
5) Confidence 0.79 Published 1991 Journal Biol. Psychiatry Section Abstract Doc Link 1912129 Disease Relevance 0.08 Pain Relevance 0.62
We examined the effect of daytime sleep on GH secretion in normal men taking placebo or clonidine orally, using a two-group blind design (placebo, clonidine; n = 9 each).
Localization (secretion) of GH associated with clonidine
6) Confidence 0.79 Published 1990 Journal Psychoneuroendocrinology Section Abstract Doc Link 2195577 Disease Relevance 0 Pain Relevance 0.49
Sleep, clonidine, and their interactive effect on growth hormone secretion in normal men.
Localization (secretion) of growth hormone associated with clonidine
7) Confidence 0.79 Published 1990 Journal Psychoneuroendocrinology Section Title Doc Link 2195577 Disease Relevance 0 Pain Relevance 0.57
Central alpha 2-adrenergic function is often inferred from the growth hormone (GH) response to clonidine, despite the drug's known hypnotic effect and the accepted cholinergic mechanism for sleep-related GH secretion.
Localization (secretion) of GH associated with clonidine
8) Confidence 0.79 Published 1990 Journal Psychoneuroendocrinology Section Abstract Doc Link 2195577 Disease Relevance 0 Pain Relevance 0.43
This response is known to be blunted in depression, and neurochemical changes observed in senile dementia of the Alzheimer type (SDAT) could lead to an up-regulation of GH secretion.
Localization (secretion) of GH associated with dementia and depression
9) Confidence 0.79 Published 1989 Journal Psychiatry Res Section Abstract Doc Link 2710869 Disease Relevance 0.53 Pain Relevance 0.26
Clonidine-induced growth hormone secretion in elderly patients with senile dementia of the Alzheimer type and major depressive disorder.
Localization (secretion) of growth hormone associated with depression, dementia and clonidine
10) Confidence 0.79 Published 1989 Journal Psychiatry Res Section Title Doc Link 2710869 Disease Relevance 0.55 Pain Relevance 0.28
Together with studies on GH basal secretion in Alzheimer's disease, this finding suggests that the final consequence of SDAT-related changes in an accentuation of the effects of aging on GH reactivity.
Localization (secretion) of GH associated with aging and disease
11) Confidence 0.79 Published 1989 Journal Psychiatry Res Section Abstract Doc Link 2710869 Disease Relevance 0.70 Pain Relevance 0.25
The effects of prolonged administration of clonidine on GH secretion thus differ markedly from the effects of acute administration as in non diabetic subjects.
Localization (secretion) of GH associated with diabetes mellitus and clonidine
12) Confidence 0.79 Published 1982 Journal Diabete Metab Section Abstract Doc Link 7160519 Disease Relevance 0.49 Pain Relevance 0.62
In chronic administration, the effects of clonidine on GH secretion are not well documented.
Localization (secretion) of GH associated with clonidine
13) Confidence 0.79 Published 1982 Journal Diabete Metab Section Abstract Doc Link 7160519 Disease Relevance 0.44 Pain Relevance 0.53
Bromocriptine may correct cardiac dysfunction and carpal tunnel syndrome in acromegaly either by reduction of GH oversecretion or by a direct effect of bromocriptine on dopamine receptors in the heart and peripheral nerve endings.
Localization (oversecretion) of GH in peripheral nerve associated with acromegaly, dopamine receptor and carpal tunnel syndrome
14) Confidence 0.79 Published 1980 Journal JAMA Section Abstract Doc Link 7420685 Disease Relevance 0.51 Pain Relevance 0.30
Effect of fluoxetine on dexamethasone-induced growth hormone release in depression: a double-blind, placebo-controlled study.
Localization (release) of growth hormone associated with depression, dexamethasone and fluoxetine
15) Confidence 0.79 Published 1995 Journal Am J Psychiatry Section Title Doc Link 7694914 Disease Relevance 0.10 Pain Relevance 0.34
CONCLUSIONS: Clinical recovery was associated with an increase in GH release in response to dexamethasone.


Localization (release) of GH
16) Confidence 0.79 Published 1995 Journal Am J Psychiatry Section Body Doc Link 7694914 Disease Relevance 0 Pain Relevance 0
We have attempted to evaluate the relationship between spontaneous growth hormone (GH) secretion and the response to GH therapy as well as the effect of discontinuation of GH therapy on further growth.
Localization (secretion) of GH
17) Confidence 0.79 Published 1996 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 8855820 Disease Relevance 0 Pain Relevance 0.08
Sumatriptan-induced growth hormone release in patients with major depression, mania, and normal controls.
Localization (release) of growth hormone associated with sumatriptan, manic depressive disorder and depression
18) Confidence 0.79 Published 1997 Journal Neuropsychopharmacology Section Title Doc Link 9326750 Disease Relevance 0.56 Pain Relevance 0.56
Reduced basal GH release would suggest an overall hypo-active GH system rather than a specific alpha-adrenergic abnormality.
Localization (release) of GH
19) Confidence 0.79 Published 2005 Journal Psychoneuroendocrinology Section Abstract Doc Link 15358444 Disease Relevance 0.16 Pain Relevance 0.09
Treatment may have reduced nocturnal GH release slightly, but treated patients still did not differ from controls.
Localization (release) of GH
20) Confidence 0.79 Published 2005 Journal Psychoneuroendocrinology Section Body Doc Link 15358444 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox