INT189303

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Atp6v1e1, TPH1) endosome (Atp6v1e1) transport (Atp6v1e1)
mitochondrion (Atp6v1e1) small molecule metabolic process (TPH1) cellular nitrogen compound metabolic process (TPH1)
Anatomy Link Frequency
body 2
Atp6v1e1 (Mus musculus)
TPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 91 98.72 Very High Very High Very High
antagonist 3 79.76 Quite High
Central nervous system 13 72.96 Quite High
Neurotransmitter 2 69.84 Quite High
5HT 3 67.48 Quite High
Multiple sclerosis 14 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Kinase C 7 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Fibrositis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coagulation Disorder 11 82.16 Quite High
Increased Venous Pressure Under Development 9 81.64 Quite High
Endometriosis (extended) 26 48.36 Quite Low
Lifespan 3 28.80 Quite Low
Breast Cancer 21 5.00 Very Low Very Low Very Low
Demyelinating Disease 14 5.00 Very Low Very Low Very Low
Myocardial Infarction 13 5.00 Very Low Very Low Very Low
Depression 8 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Hot Flashes 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, E2 increases production of tryptophan hydroxylase[18,19] (TPH, the rate-limiting step in synthesis of serotonin from tryptophan), increasing the concentrations of serotonin in the body [20,21].
E2 Positive_regulation (increases) of Gene_expression (production) of tryptophan hydroxylase in body associated with serotonin
1) Confidence 0.01 Published 2005 Journal BMC Womens Health Section Body Doc Link PMC1327664 Disease Relevance 0.16 Pain Relevance 0.73

General Comments

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