INT189427

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Context Info
Confidence 0.16
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.23
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
FAAH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Endocannabinoid 44 79.20 Quite High
Neuropathic pain 17 68.96 Quite High
Spinal cord 16 67.76 Quite High
Pain 19 56.56 Quite High
Spinal sensitization 1 55.24 Quite High
Peripheral nerve injury 1 38.64 Quite Low
descending inhibitory control 1 27.72 Quite Low
substance P 1 24.56 Low Low
Periaqueductal grey 7 19.40 Low Low
Hippocampus 4 18.32 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 29 68.96 Quite High
Pain 26 56.56 Quite High
Nervous System Injury 1 38.64 Quite Low
Lyme Disease 2 30.80 Quite Low
Urological Neuroanatomy 7 19.40 Low Low
Nociception 15 17.76 Low Low
INFLAMMATION 11 14.84 Low Low
Injury 8 12.20 Low Low
Inflammatory Pain 9 10.32 Low Low
Infection 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FAAH2 appears to be poorly expressed, if at all, in the brain. 2-AG is mainly metabolised by MAGL to arachidonic acid and glycerol [105,106].
Gene_expression (expressed) of FAAH2 in brain
1) Confidence 0.16 Published 2009 Journal Mol Pain Section Body Doc Link PMC2770047 Disease Relevance 0.23 Pain Relevance 0.42
Genes in this group include those encoding putative detoxification or resistance function for toxins (e.g., BMA1038 putative penicillin amidase and BMA0952 NodT family RND efflux system), secondary metabolite biosynthesis (e.g., BMA1123 peptide synthetase and BMAA1202 polyketide synthase), some TTSS genes (e.g., BMAA1617 putative hrp protein and BMAA1619 hypothetical protein), and cell envelope synthesis genes (e.g., BMAA0751 N-acetylmuramoyl-L-alanine amidase domain protein, BMAA1498 putative O-antigen acetylase, BMAA1986 ADP-heptose-LPS heptosyltransferase II, BMAA1987 glycosyl transferase).
Gene_expression (synthesis) of amidase domain protein
2) Confidence 0.01 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1343551 Disease Relevance 0 Pain Relevance 0
Genes in this group include those encoding putative detoxification or resistance function for toxins (e.g., BMA1038 putative penicillin amidase and BMA0952 NodT family RND efflux system), secondary metabolite biosynthesis (e.g., BMA1123 peptide synthetase and BMAA1202 polyketide synthase), some TTSS genes (e.g., BMAA1617 putative hrp protein and BMAA1619 hypothetical protein), and cell envelope synthesis genes (e.g., BMAA0751 N-acetylmuramoyl-L-alanine amidase domain protein, BMAA1498 putative O-antigen acetylase, BMAA1986 ADP-heptose-LPS heptosyltransferase II, BMAA1987 glycosyl transferase).
Gene_expression (biosynthesis) of amidase domain protein
3) Confidence 0.01 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1343551 Disease Relevance 0 Pain Relevance 0

General Comments

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