INT189476

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 2005
Last Reported 2006
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.79
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Tuba1a) cytoskeleton (Tuba1a) GTPase activity (Tuba1a)
protein complex (Tuba1a) cytoplasm (Tuba1a)
Anatomy Link Frequency
neuronal 1
neuron 1
Tuba1a (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 2 98.32 Very High Very High Very High
Eae 22 94.88 High High
Pain 18 89.16 High High
withdrawal 4 84.40 Quite High
intrathecal 12 65.92 Quite High
Dorsal horn neuron 12 53.28 Quite High
Thermal hyperalgesia 38 50.00 Quite Low
nociceptor 2 49.76 Quite Low
Lasting pain 4 46.04 Quite Low
glial activation 2 41.40 Quite Low
Disease Link Frequency Relevance Heat
Infection 86 94.60 High High
Nociception 38 93.44 High High
Inflammatory Pain 16 92.88 High High
Pain 24 89.16 High High
Malaria 96 50.80 Quite High
Hyperalgesia 42 50.00 Quite Low
INFLAMMATION 44 36.36 Quite Low
Adhesions 8 28.12 Quite Low
Cv General 3 Under Development 4 25.84 Quite Low
Neuropathic Pain 4 19.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RANTES protein expression was normalized to that of alpha-tubulin.


Gene_expression (expression) of alpha-tubulin
1) Confidence 0.65 Published 2005 Journal Malar J Section Body Doc Link PMC1343570 Disease Relevance 0.06 Pain Relevance 0.05
We tested mutant mice that express dominant negative MEK, whose expression was driven by the pan-neuronal and neuron-specific Talpha1 alpha-tubulin promoter, such that the dominant negative MEK protein is expressed only in neurons.
Neg (negative) Gene_expression (expressed) of Talpha1 alpha-tubulin promoter in neuron
2) Confidence 0.24 Published 2006 Journal Mol Pain Section Body Doc Link PMC1382249 Disease Relevance 0.55 Pain Relevance 0.45
We tested mutant mice that express dominant negative MEK, whose expression was driven by the pan-neuronal and neuron-specific Talpha1 alpha-tubulin promoter, such that the dominant negative MEK protein is expressed only in neurons.
Neg (negative) Gene_expression (expressed) of Talpha1 alpha-tubulin promoter in neuronal
3) Confidence 0.08 Published 2006 Journal Mol Pain Section Body Doc Link PMC1382249 Disease Relevance 0.55 Pain Relevance 0.45
Expression of alpha-tubulin protein from sample to sample was within 5% of the mean expression level in both infected and uninfected samples throughout the course of the infection.


Gene_expression (Expression) of alpha-tubulin protein associated with infection
4) Confidence 0.03 Published 2005 Journal Malar J Section Body Doc Link PMC1343570 Disease Relevance 0.63 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox