INT189484

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Context Info
Confidence 0.19
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ccr3) signal transduction (Ccr3) extracellular space (Ccr3)
plasma membrane (Ccr3) signal transducer activity (Ccr3)
Ccr3 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 36 100.00 Very High Very High Very High
cytokine 6 97.64 Very High Very High Very High
Neurotransmitter 2 91.28 High High
cva 2 72.72 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 4 99.56 Very High Very High Very High
Stress 1 89.16 High High
Infection 43 82.84 Quite High
Pressure And Volume Under Development 3 77.36 Quite High
Cv General 3 Under Development 2 72.72 Quite High
Cerebral Malaria 39 63.12 Quite High
Coma 3 59.60 Quite High
Convulsion 4 59.24 Quite High
Paralysis 2 58.72 Quite High
Ataxia 2 57.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Marked alterations in expressio n of immunomodulator mRNA, including C-C chemokine RANTES, C-C chemokine receptors CCR1, CCR3 and CCR5, adhesion molecules PECAM-1, ICAM-1, and VCAM-1, cytokines IF N-gamma, TNF-alpha, IL-12, IL-4, and iNOS were observed to be up-regulated, while growth factors, GDF-2 and TGF-beta precursor, were down-regulated (Table 2, P < 0.05) at peak parasitaemia.


Regulation (alterations) of CCR3 associated with chemokine, adhesions and cytokine
1) Confidence 0.19 Published 2005 Journal Malar J Section Body Doc Link PMC1343570 Disease Relevance 1.07 Pain Relevance 0.23

General Comments

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