INT18954

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Context Info
Confidence 0.09
First Reported 1982
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 8.31
Pain Relevance 3.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (OLAH)
Anatomy Link Frequency
joint 1
plasma 1
leukocyte 1
erythrocyte 1
OLAH (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 103 100.00 Very High Very High Very High
Inflammation 12 100.00 Very High Very High Very High
psoriasis 5 99.84 Very High Very High Very High
rheumatoid arthritis 117 99.82 Very High Very High Very High
backache 1 99.24 Very High Very High Very High
tolerance 2 99.00 Very High Very High Very High
spondylitis 1 97.96 Very High Very High Very High
aspirin 4 97.80 Very High Very High Very High
peptic ulcer disease 1 94.72 High High
cINOD 4 93.44 High High
Disease Link Frequency Relevance Heat
Arthritis 90 100.00 Very High Very High Very High
Seronegative Spondarthritis 15 100.00 Very High Very High Very High
INFLAMMATION 9 99.92 Very High Very High Very High
Arthropathy 6 99.90 Very High Very High Very High
Psoriasis 6 99.84 Very High Very High Very High
Rheumatoid Arthritis 117 99.82 Very High Very High Very High
Low Back Pain 6 99.40 Very High Very High Very High
Congenital Anomalies 1 99.24 Very High Very High Very High
Rheumatic Diseases 4 98.94 Very High Very High Very High
Inflammatory Bowel Disease 3 95.24 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A prospective phase II trial was conducted to assess the feasibility, tolerance, and efficacy of a device designed for selective removal of rheumatoid factor from the plasma of rheumatoid arthritis patients.
Negative_regulation (removal) of rheumatoid factor in plasma associated with rheumatoid arthritis and tolerance
1) Confidence 0.09 Published 1991 Journal Transfusion Section Abstract Doc Link 1996481 Disease Relevance 0.25 Pain Relevance 0.17
Selective in vivo removal of rheumatoid factor by an extracorporeal treatment device in rheumatoid arthritis patients.
Negative_regulation (removal) of rheumatoid factor associated with rheumatoid arthritis
2) Confidence 0.06 Published 1991 Journal Transfusion Section Title Doc Link 1996481 Disease Relevance 0.50 Pain Relevance 0.18
RESULTS: The 5 subsets of SpA share many clinical, immunohistochemical, and genetic features, including the common presence of human leukocyte antigen-B27 and the absence of rheumatoid factor.
Negative_regulation (absence) of rheumatoid factor in leukocyte
3) Confidence 0.06 Published 2008 Journal Semin. Arthritis Rheum. Section Body Doc Link 18166219 Disease Relevance 0.09 Pain Relevance 0
In contrast, the treatment led to a reduction in the total amount of rheumatoid factor.
Negative_regulation (reduction) of rheumatoid factor
4) Confidence 0.05 Published 1984 Journal Inflammation Section Abstract Doc Link 6480068 Disease Relevance 0.32 Pain Relevance 0.15
They are characterized by an association with the cell surface antigen HLA-B27, sacroilitis and spondylitis, inflammatory peripheral arthritis, enthesopathy (abnormalities in ligamentous attachments), and the absence of rheumatoid factor.
Negative_regulation (absence) of rheumatoid factor associated with spondylitis, inflammation, congenital anomalies, rheumatic diseases and arthritis
5) Confidence 0.03 Published 1984 Journal Prim. Care Section Abstract Doc Link 6332327 Disease Relevance 0.96 Pain Relevance 0.43
The erythrocyte sedimentation rate, the rheumatoid factor titer, and alkaline phosphatase were significantly reduced in the benoxaprofen patient group.
Negative_regulation (reduced) of rheumatoid factor in erythrocyte
6) Confidence 0.03 Published 1982 Journal Eur J Rheumatol Inflamm Section Abstract Doc Link 7084281 Disease Relevance 0.68 Pain Relevance 0.39
Characteristics associated with natural or drug-induced remission in RA are the absence of anti-CCP antibodies/rheumatoid factor, a low number of swollen joints and a low level of radiological joint destruction at baseline [16-18].
Negative_regulation (absence) of rheumatoid factor in joint associated with rheumatoid arthritis
7) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779387 Disease Relevance 1.00 Pain Relevance 0.35
At presentation, 330 patients had an UA and after one year follow-up about one-third of these patients was in remission (persistent absence of arthritis at examination) and, therefore, were discharged from the outpatient clinic [8].
Spec (examination) Negative_regulation (absence) of arthritis associated with arthritis
8) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779387 Disease Relevance 1.22 Pain Relevance 0.61
The characteristic features of spondylo-arthropathies are absence of rheumatoid factor, inflammatory low backache, sacro-iliitis, peripheral arthritis, enthesopathy, tendency to familial aggregation and association with HLA-B27.
Negative_regulation (absence) of rheumatoid factor associated with low back pain, inflammation, arthropathy, rheumatic diseases, arthritis and backache
9) Confidence 0.00 Published 2003 Journal J Indian Med Assoc Section Abstract Doc Link 15168985 Disease Relevance 1.96 Pain Relevance 0.74
Psoriatic arthritis (PsA) is a common form of inflammatory arthritis but is underdiagnosed.
Negative_regulation (underdiagnosed) of arthritis associated with seronegative spondarthritis, inflammation and arthritis
10) Confidence 0.00 Published 2009 Journal Practitioner Section Abstract Doc Link 20120827 Disease Relevance 1.34 Pain Relevance 0.65

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