INT189550

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.68
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PAH) small molecule metabolic process (PAH) plasma membrane (BMPR2)
cellular nitrogen compound metabolic process (PAH) cytoplasm (BMPR2)
Anatomy Link Frequency
germline 2
BMPR2 (Homo sapiens)
PAH (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 4 76.16 Quite High
metalloproteinase 10 5.00 Very Low Very Low Very Low
Serotonin 10 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 170 100.00 Very High Very High Very High
Disease 28 91.40 High High
Telangiectasia 2 85.28 High High
Myocardial Infarction 2 81.24 Quite High
Fibrosis 4 76.16 Quite High
Hypertrophy 2 75.44 Quite High
Hypoxia 18 5.00 Very Low Very Low Very Low
Adhesions 12 5.00 Very Low Very Low Very Low
Hypersensitivity 12 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
About 50% of these PAH families have been shown to have mutations in the bone morphogenetic protein receptor-II gene (BMPR2), but only 10% of cases of the sporadic or idiopathic form of PAH are associated with germline mutations in BMPR2 [2].
BMPR2 Binding (associated) of PAH in germline associated with pulmonary hypertension
1) Confidence 0.06 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 1.34 Pain Relevance 0.04
About 50% of these PAH families have been shown to have mutations in the bone morphogenetic protein receptor-II gene (BMPR2), but only 10% of cases of the sporadic or idiopathic form of PAH are associated with germline mutations in BMPR2 [2].
BMPR2 Binding (associated) of PAH in germline associated with pulmonary hypertension
2) Confidence 0.06 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 1.34 Pain Relevance 0.04

General Comments

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