INT189577

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Context Info
Confidence 0.31
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EGLN1) nucleus (EGLN1) cytoplasm (EGLN1)
EGLN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 10 5.00 Very Low Very Low Very Low
Serotonin 10 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 18 99.98 Very High Very High Very High
Hypertension 4 99.14 Very High Very High Very High
Cancer 10 97.08 Very High Very High Very High
Pulmonary Hypertension 170 89.08 High High
Increased Venous Pressure Under Development 2 83.92 Quite High
Metastasis 2 60.24 Quite High
Lung Cancer 2 58.56 Quite High
Adhesions 12 45.56 Quite Low
Coagulation Disorder 2 20.32 Low Low
Disease 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the drug hydralazine is a vasodilator used in the treatment of severe hypertension and one of its mechanisms of action is to inhibit the enzymatic activity of PHD2 [45].
Negative_regulation (inhibit) of PHD2 associated with hypertension
1) Confidence 0.31 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 0.79 Pain Relevance 0
Under hypoxia PHD2 activity is decreased and HIF-1?
Negative_regulation (decreased) of PHD2 associated with hypoxia
2) Confidence 0.31 Published 2006 Journal Respir Res Section Body Doc Link PMC1351173 Disease Relevance 0.94 Pain Relevance 0

General Comments

This test has worked.

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