INT189610

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (NEK1) nucleolus (NEK1) cytoskeleton (NEK1)
nucleus (NEK1) cell cycle (NEK1) cell division (NEK1)
Anatomy Link Frequency
muscle cells 1
NEK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 5 91.96 High High
Oxycodone 26 66.84 Quite High
methadone 13 62.92 Quite High
Opioid 3 50.00 Quite Low
Serotonin 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 85 89.20 High High
Disease 14 52.88 Quite High
Hypoxia 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Reflex Sympathetic Dystrophy 3 5.00 Very Low Very Low Very Low
Fibrosis 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Four of the up regulated genes, magic roundabout, hevin, thrombomodulin and sucrose non-fermenting protein-related kinase-1 are expressed specifically by endothelial cells and one, muscleblind-1, by muscle cells, suggesting that they may be associated with plexiform lesions and hypertrophic arterial wall remodelling, respectively.



Gene_expression (expressed) of non-fermenting protein-related kinase-1 in muscle cells
1) Confidence 0.03 Published 2006 Journal Respir Res Section Abstract Doc Link PMC1351173 Disease Relevance 0.47 Pain Relevance 0.05
Concentrations of Pharmaceuticals Downstream of NY1, NY2, and NY3 Effluents
Gene_expression (Concentrations) of NY1
2) Confidence 0.01 Published 2010 Journal Environmental Science & Technology Section Body Doc Link PMC2893609 Disease Relevance 0 Pain Relevance 0.13

General Comments

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