INT189646

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CHKB, ASAP1, DAG1) nucleoplasm (DAG1) signal transduction (ASAP1)
extracellular space (DAG1) extracellular region (DAG1) nucleus (DAG1)
CHKB (Homo sapiens)
ASAP1 (Homo sapiens)
DAG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 47 100.00 Very High Very High Very High
agonist 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 15.60 Low Low
Cancer 16 5.00 Very Low Very Low Very Low
Aging 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Cervical Cancer 1 5.00 Very Low Very Low Very Low
Genetic Translocation 1 5.00 Very Low Very Low Very Low
Chromosomal Instability 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To explain this, it was speculated that Receptor Ck could inhibit PKC by blocking the production of DAG either by inhibiting the enzyme PAP, which catalyses the conversion of PA to DAG or by activating the enzyme diacylglycerol kinase (DAGK) which catalyses the conversion of DAG back to PA.
Ck Negative_regulation (inhibiting) of PAP Negative_regulation (blocking) of Gene_expression (production) of DAG associated with kinase c
1) Confidence 0.04 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0 Pain Relevance 0.24

General Comments

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