INT189679

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 1.00
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TERT) DNA binding (TERT) cytoplasm (TERT)
RNA binding (TERT) chromosome (TERT) nucleolus (TERT)
INSRR (Homo sapiens)
TERT (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 329 52.56 Quite High
Central nervous system 7 27.16 Quite Low
agonist 28 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 112 86.20 High High
Squamous Cell Carcinoma 7 62.36 Quite High
Reprotox - General 1 14 59.64 Quite High
Disorder Of Lipid Metabolism 7 57.04 Quite High
Genetic Translocation 7 55.48 Quite High
Repression 28 5.00 Very Low Very Low Very Low
Aging 28 5.00 Very Low Very Low Very Low
Apoptosis 21 5.00 Very Low Very Low Very Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low
Hyperplasia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Keeping in view the established link among Receptor Ck, Bcl-2 and cyclin D [22], it was reasonable to speculate that cyclin D and Bcl-2 could mediate the effect of Receptor Ck on hTERT gene transcription.
Receptor Regulation (effect) of Transcription (transcription) of hTERT
1) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0 Pain Relevance 0
Our results revealed a novel mechanism for the regulation of hTERT transcription controlled by cholesterol activated Receptor Ck.


Receptor Regulation (controlled) of Transcription (transcription) of hTERT
2) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0.37 Pain Relevance 0
In order to determine whether cholesterol-activated Receptor Ck regulates the transcription of hTERT, c-myc and PPAR?
Receptor Regulation (regulates) of Transcription (transcription) of hTERT
3) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0.18 Pain Relevance 0
Role of Bcl-2 and cyclin D in Receptor Ck dependent regulation of hTERT gene transcription
Receptor Regulation (regulation) of Transcription (transcription) of hTERT
4) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0.06 Pain Relevance 0
Role of c-myc in Receptor Ck dependent regulation of hTERT gene transcription
Receptor Regulation (regulation) of Transcription (transcription) of hTERT
5) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0 Pain Relevance 0
Involvement of Receptor Ck in the transcription of hTERT, c-myc and PPAR?
Receptor Regulation (Involvement) of Transcription (transcription) of hTERT
6) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0.31 Pain Relevance 0
Receptor Ck-dependent signaling regulates hTERT gene transcription

Background

Receptor Regulation (regulates) of Transcription (transcription) of hTERT
7) Confidence 0.00 Published 2006 Journal BMC Cell Biol Section Title Doc Link PMC1351175 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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