INT189690

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (USF1, TERT) nucleoplasm (TERT) DNA binding (TERT)
enzyme binding (USF1) cytoplasm (TERT) RNA binding (TERT)
Anatomy Link Frequency
finger 1
USF1 (Homo sapiens)
TERT (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 47 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 16 100.00 Very High Very High Very High
Apoptosis 3 93.28 High High
Papillomavirus Infection 1 57.28 Quite High
Hepatitis 1 55.28 Quite High
Aging 4 47.68 Quite Low
Repression 4 45.44 Quite Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Cervical Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B) and upstream stimulatory factors (USF) have been shown to upregulate hTERT transcription whereas transcription factors like Mad1, Wilms' tumor 1 (WT1) tumor suppressor protein, E2F, p53 and myeloid cell-specific zinc finger protein-2 (MZF-2) have been found to down-regulate hTERT transcription [7-9].
USF Regulation (regulate) of hTERT in finger associated with cancer
1) Confidence 0.05 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0.46 Pain Relevance 0

General Comments

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