INT189750

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Context Info
Confidence 0.26
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.36
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CHKB)
Anatomy Link Frequency
muscle 2
CHKB (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 47 98.84 Very High Very High Very High
Inflammation 8 55.68 Quite High
Catecholamine 4 54.32 Quite High
Action potential 11 40.08 Quite Low
Central nervous system 3 38.72 Quite Low
Peripheral nervous system 1 36.64 Quite Low
abdominal pain 2 20.32 Low Low
Pain 1 19.64 Low Low
corticosteroid 24 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 3 99.90 Very High Very High Very High
Ectopic Pregnancy 95 99.52 Very High Very High Very High
Cardiovascular Disorder Under Development 17 94.52 High High
Apoptosis 10 87.48 High High
Muscle Disease 91 86.24 High High
Neuropathy 80 86.08 High High
Muscle Weakness 2 82.96 Quite High
Critical Illness 21 80.48 Quite High
Injury 2 73.68 Quite High
Tubal Pregnancy 10 67.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ROC curves demonstrated significant discriminatory capability of increased CK for EP diagnosis, suggesting that CK concentrations could be used to predict EP.42
Negative_regulation (used) of Positive_regulation (concentrations) of CK associated with ectopic pregnancy
1) Confidence 0.26 Published 2008 Journal Clinics Section Body Doc Link PMC2664731 Disease Relevance 1.10 Pain Relevance 0.03
To further verify the involvement of PKC in the Receptor Ck signaling pathway, the effect of PKC inhibitor was investigated in a situation where Receptor Ck activation was blocked.
Negative_regulation (blocked) of Positive_regulation (activation) of Ck associated with kinase c
2) Confidence 0.23 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1351175 Disease Relevance 0 Pain Relevance 0.32
Even in patients with overt muscle necrosis, an increase in CK is often transient and can be missed.
Negative_regulation (missed) of Positive_regulation (increase) of CK in muscle associated with necrosis
3) Confidence 0.14 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 0.95 Pain Relevance 0
When all courses were taken together, an increase in ANP and CK-MB occurred after DXR.
Negative_regulation (occurred) of Positive_regulation (increase) of CK-MB
4) Confidence 0.06 Published 2008 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2515587 Disease Relevance 0.31 Pain Relevance 0.03

General Comments

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