INT189878

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Context Info
Confidence 0.56
First Reported 2006
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdh1) Golgi apparatus (Cdh1) plasma membrane (Cdh1)
cytoplasm (Cdh1)
Anatomy Link Frequency
plasma 1
Cdh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 5 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 18 83.64 Quite High
Disease 8 79.64 Quite High
Apoptosis 10 55.00 Quite High
Adhesions 61 43.76 Quite Low
Infection 42 5.00 Very Low Very Low Very Low
Sprains And Strains 16 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Sepsis 4 5.00 Very Low Very Low Very Low
Gastroenteritis 2 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, it was reported that E-cadherin that had not bound to catenin complex was not transported to the plasma membrane, but was instead degraded in lysosomes [16].
Neg (not) Localization (transported) of E-cadherin in plasma
1) Confidence 0.56 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875860 Disease Relevance 0.21 Pain Relevance 0
For instance, tight junction strand remodeling could result in a local loss in fence function, and localization of E-cadherin above the tight junctions.
Localization (localization) of E-cadherin
2) Confidence 0.13 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1354196 Disease Relevance 0.06 Pain Relevance 0
We determined that L. monocytogenes does not actively disrupt the tight junctions, but finds E-cadherin at a morphologically distinct subset of intercellular junctions.
Spec (finds) Localization (finds) of E-cadherin
3) Confidence 0.12 Published 2006 Journal PLoS Pathogens Section Abstract Doc Link PMC1354196 Disease Relevance 0.08 Pain Relevance 0

General Comments

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