INT189949

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Context Info
Confidence 0.60
First Reported 2006
Last Reported 2006
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 6.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Pttg1) chromosome organization (Pttg1) chromosome segregation (Pttg1)
nucleus (Pttg1) cell cycle (Pttg1) cell division (Pttg1)
Anatomy Link Frequency
lung 4
Pttg1 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 12 36.12 Quite Low
addiction 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 120 99.84 Very High Very High Very High
Small Cell Lung Cancer 114 99.84 Very High Very High Very High
Cancer 288 99.60 Very High Very High Very High
Non-small-cell Lung Cancer 156 99.04 Very High Very High Very High
Metastasis 72 98.88 Very High Very High Very High
Leukemia 12 98.68 Very High Very High Very High
Gastrointestinal Neoplasms 6 97.76 Very High Very High Very High
Skin Cancer 18 96.80 Very High Very High Very High
Pituitary Cancer 24 96.28 Very High Very High Very High
Apoptosis 24 96.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we examined the prognostic value of PTTG-1 expression for survival in relationship to the different histological subtypes of lung cancer.
Spec (examined) Regulation (value) of Gene_expression (expression) of PTTG-1 in lung associated with lung cancer
1) Confidence 0.60 Published 2006 Journal J Carcinog Section Body Doc Link PMC1360069 Disease Relevance 1.07 Pain Relevance 0
In order to evaluate the proportion of PTTG-1 expression in SCLC: tumors with ?
Regulation (proportion) of Gene_expression (expression) of PTTG-1 associated with cancer and small cell lung cancer
2) Confidence 0.44 Published 2006 Journal J Carcinog Section Body Doc Link PMC1360069 Disease Relevance 0.68 Pain Relevance 0
Performing RT-PCR for the detection of PTTG-1 mRNA Honda et al. detected PTTG-1 expression in 12 out of 14 NSCLCs.
Regulation (detected) of Gene_expression (expression) of PTTG-1
3) Confidence 0.44 Published 2006 Journal J Carcinog Section Body Doc Link PMC1360069 Disease Relevance 1.19 Pain Relevance 0
In this study, we examined the role of PTTG-1 expression in lung cancer with regard to histological subtype, the correlation of PTTG-1 to clinical parameters and relation on patients' survival.


Spec (examined) Regulation (role) of Gene_expression (expression) of PTTG-1 in lung associated with lung cancer
4) Confidence 0.27 Published 2006 Journal J Carcinog Section Abstract Doc Link PMC1360069 Disease Relevance 1.39 Pain Relevance 0
To examine the influence of PTTG-1 expression as an independent prognostic factor for unresectable NSCLC patients multivariate analysis was performed.
Spec (examine) Regulation (influence) of Spec (examine) Gene_expression (expression) of PTTG-1 associated with non-small-cell lung cancer
5) Confidence 0.27 Published 2006 Journal J Carcinog Section Body Doc Link PMC1360069 Disease Relevance 0.79 Pain Relevance 0
The intensity of PTTG-1 expression as well as the proportion of PTTG-1 positive cells within a tumor was used for univariate and multivariate analysis.


Regulation (intensity) of Gene_expression (expression) of PTTG-1 associated with cancer
6) Confidence 0.27 Published 2006 Journal J Carcinog Section Abstract Doc Link PMC1360069 Disease Relevance 1.72 Pain Relevance 0

General Comments

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