INT189954

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.03
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TCEAL1)
Anatomy Link Frequency
adipocyte 2
lung 2
TCEAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 1 80.56 Quite High
agonist 33 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 21 99.68 Very High Very High Very High
Breast Cancer 8 96.00 Very High Very High Very High
Apoptosis 24 94.48 High High
Death 3 86.08 High High
Obesity 17 85.96 High High
Cancer 94 85.36 High High
Non-small-cell Lung Cancer 29 85.36 High High
Repression 2 78.64 Quite High
Carcinoma 2 70.88 Quite High
Small Cell Lung Cancer 19 68.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Terminal adipocyte differentiation is accompanied by expression of proteins that repress RNA expression, along with induction of p21, leading to irreversible loss of proliferative potential [140, 143].
Negative_regulation (repress) of Positive_regulation (induction) of p21 in adipocyte
1) Confidence 0.07 Published 2010 Journal PPAR Research Section Body Doc Link PMC2825651 Disease Relevance 0.73 Pain Relevance 0.04
Further, PTTG-1 overexpression in the human lung cancer cell line A549 inhibited the cell growth via activation of p21 [20].
Negative_regulation (inhibited) of Positive_regulation (activation) of p21 in lung associated with lung cancer
2) Confidence 0.02 Published 2006 Journal J Carcinog Section Body Doc Link PMC1360069 Disease Relevance 1.29 Pain Relevance 0

General Comments

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