INT189959

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 4.88
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (SENP8)
SENP8 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 36 100.00 Very High Very High Very High
cytokine 42 99.16 Very High Very High Very High
cva 18 84.80 Quite High
abdominal pain 12 5.00 Very Low Very Low Very Low
headache 7 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 343 100.00 Very High Very High Very High
Viral Meningitis 54 100.00 Very High Very High Very High
Dengue Hemorrhagic Fever 290 98.84 Very High Very High Very High
Fever 35 88.48 High High
Cv General 3 Under Development 18 84.80 Quite High
Syndrome 8 84.16 Quite High
Dengue 357 83.80 Quite High
Sprains And Strains 8 71.28 Quite High
Mental Disorders 1 66.44 Quite High
Severe Acute Respiratory Syndrome 6 62.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using a cytospin system (Auto smear, CF-12DE, SAKURA, Japan) three smears were made on separate glass slides from each of the 50 specimens, one each for JE, WN and Den-2 virus respectively. 150 ?
Positive_regulation (one) of Gene_expression (virus) of Den-2 associated with viral meningitis
1) Confidence 0.30 Published 2006 Journal Virol J Section Body Doc Link PMC1360082 Disease Relevance 0.72 Pain Relevance 0
CLEC5A-mediated DEN infection in animals that was susceptible to DEN hemorrhagic infection also revealed augmented immune response [40].
Positive_regulation (susceptible) of Gene_expression (infection) of DEN associated with infection
2) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.56 Pain Relevance 0
With both genotypes, the viral replication 24 h post DEN infection increased significantly more in the presence of neutralizing antibody than in the absence of neutralizing antibody (p?
Positive_regulation (increased) of Gene_expression (infection) of DEN associated with infection
3) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.44 Pain Relevance 0
CLEC5A-mediated DEN infection in animals that was susceptible to DEN hemorrhagic infection also revealed augmented immune response [40].
Positive_regulation (mediated) of Gene_expression (infection) of DEN associated with infection
4) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.55 Pain Relevance 0
CLEC5A-mediated DEN infection in animals that was susceptible to DEN hemorrhagic infection also revealed augmented immune response [40].
Positive_regulation (susceptible) of Gene_expression (infection) of DEN associated with infection
5) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.56 Pain Relevance 0
, IL-12p40, and chemokine IP-10 production in DEN-infected MDDCs with AG genotype of rs4804803
Positive_regulation (chemokine) of Gene_expression (production) of DEN associated with chemokine
6) Confidence 0.09 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 0.64 Pain Relevance 0.19
Our results suggest that humans carrying the rs4804803 AG genotype have a higher DC-SIGN expression and lower DEN-2 replication in MDDCs.
Positive_regulation (higher) of Gene_expression (expression) of DEN
7) Confidence 0.08 Published 2011 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC3014977 Disease Relevance 1.41 Pain Relevance 0.04

General Comments

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