INT190015

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.41
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Msh2) ATPase activity (Msh2) nucleus (Msh2)
enzyme binding (Msh2) cell cycle (Msh2) DNA binding (Msh2)
Anatomy Link Frequency
MLH1 1
Msh2 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colorectal Cancer 52 99.76 Very High Very High Very High
Cancer 232 96.68 Very High Very High Very High
Malignant Neoplastic Disease 10 87.76 High High
Apoptosis 82 78.20 Quite High
Mucositis 2 73.28 Quite High
Death 12 68.28 Quite High
Diarrhoea 2 67.20 Quite High
Endometrial Cancer 28 66.40 Quite High
Uterine Cancer 2 50.16 Quite High
Nicotine Addiction 6 36.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations in the MMR genes MLH1 and MSH2 were first identified because of their association with colorectal cancer in HNPCC families (4–7).
MSH2 Binding (association) of in MLH1 associated with colorectal cancer
1) Confidence 0.27 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.90 Pain Relevance 0
MSH2–MSH6 can specifically recognize distinct types of damaged DNA (such as those caused by oxidative or alkylating agents).
MSH2 Binding (recognize) of
2) Confidence 0.26 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1361617 Disease Relevance 0.51 Pain Relevance 0

General Comments

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